The production shut down for five months, and Applegate told the New York Times that she needed that time “to process my loss of my life, my loss of that part of me.” (As the Times notes, Applegate has further projects in development-including Sony’s animated Married.
During the filming of this season, she was diagnosed with multiple sclerosis-a chronic autoimmune disease that impacts communication between one’s brain and body. In real life, Applegate has said she wonders if Dead to Me might be her last big on-screen role.
